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The peptide world found mitochondria. Please hide your wallet. One of the up and coming peptides is one called SS-31. The pharmaceutical version has an FDA-approved lane for Barth syndrome, which is a rare mitochondrial disease. And that’s exactly why this gets messy. When something is pure supplement-rack sewer foam, it’s easy to point, laugh, and move on with your life. But SS-31 — also called elamipretide — is a real mitochondrial-targeted compound with real biology behind it. Cool mechanism. Clinical data. A narrow pharmaceutical lane. Then the peptide carnival grabs that one clean mechanism, duct-tapes it to a picture of ATP, fires up the fog machine, and tells every lifter with a credit card they’re one injection away from skyrocketing their VO2 max Is that even close to the truth though? So I put together a free PDF breaking down the whole mitochondrial crime scene: >> SS-31 PDF << no cost to you What SS-31 actually does SS-31 interacts with cardiolipin in the inner mitochondrial membrane. That matters in specific disease contexts where mitochondrial structure is compromised. Think Barth syndrome and other impaired-system situations. ...but does any of that transfer to you? Inside the free PDF, I cover the mechanism, the disease-state data, the animal studies, the human trials, the research-chemical problem, and why “better mitochondria” is great, but how you get there matters. Much love and mitochondrial mayhem, PS — Let me know what you think of this one. The first part is the shorter coach version and then the rest is the ultra nerdy version. I literally pulled every study ever done on SS-31 and after many months of tweaks and reading, the full version is finally done. No cost to you. >> SS-31 PDF << Full PDF ________ Mike T Nelson CISSN, CSCS, MSME, PhD Mike T Nelson is a PhD and not a physician or registered dietitian. The contents of this email should not be taken as medical advice. It is not intended to diagnose, treat, cure, or prevent any health problem - nor is it intended to replace the advice of a physician. Always consult your physician or qualified health professional on any matters regarding your health. .. |
Creator of the Flex Diet Cert & Phys Flex Cert, CSCS, CISSN, Assoc Professor, kiteboarder, lifter of odd objects, metal music lover. >>>>Sign up to my daily FREE Fitness Insider newsletter below
As you saw, the Flex Diet Cert slammed shut t this past Monday night and huge congrats to all of you who are enrolled this round. Wahoo! ..but if the price was too high or the wrong time, no worries as you did not get banished to the metabolic wasteland forever. Another round comes back slated for Jan or Feb 2027, and I’ll make enough noise that your neighbor’s dog will know about it. However, if you want to learn all about met flex on the cheap, you are in luck as sat down with Dr. Jeremy...
In 1990, researchers did something wonderfully deranged. They took 12 pairs of identical twins, fed each man an extra 84,000 calories over 100 days, kept them mostly sedentary, and watched the metabolic dice roll across the lab floor. Everyone gained weight. Shocker I know. Physics did not pack a suitcase, fake its own death, and move into a cave in Nepal... ..Yet the amount they gained was wildly different. One guy gained under 10 pounds. Another gained almost 30. Keep in mind this was on...
I am still reeling from another amazing ISSN conference. Good reeling. Brain full. Voice crispy. Body moving like someone replaced my normal joints with airport furniture. After a few days of presenting, talking shop, catching up with brilliant people, and pretending my nervous system is not being held together by caffeine and conference carpet, I am moving a bit slow today. Still happy as hell. Also mildly cooked. So I’ll keep this one short because the clock is loud tonight. The expanded...