The Science of Physiological Flexibility with Barbell Shrugged


In this episode of Barbell Shrugged, I had the chance to return and talk about one of my favorite topics: physiological flexibility. Anders Varner and Doug Larson asked some great questions as we dug into the four pillars I use to help people build a more resilient and adaptable physiology—temperature regulation, pH balance, expanded fuel use, and breath work.

We broke down what it means to train your body to handle extremes: staying sharp through big temperature swings, managing pH shifts from diet and exercise, tapping into different fuel sources efficiently, and using breath control as a performance tool.

These aren’t just abstract ideas—they translate directly into better performance, faster recovery, and stronger long-term health.

If you want to understand how to push your body further while making it more adaptable, this conversation is one you won’t want to miss.

In this episode:

  • 00:19 Understanding Physiological Flexibility
  • 04:42 Diving into Temperature Adaptation
  • 07:03 Heat and Cold Adaptation Strategies
  • 09:30 Practical Applications and Personal Experiences
  • 13:48 The Importance of Environmental Adaptation
  • 25:20 Exploring pH and Buffering Systems
  • 27:03 Sodium Bicarbonate: Benefits and Drawbacks
  • 27:39 Personal Experimentation with Sodium Bicarbonate
  • 28:41 Beta-Alanine vs. Sodium Bicarbonate
  • 31:37 Physiological Flexibility and Performance
  • 33:42 Cross Adaptation and Its Benefits
  • 35:43 Ketones and Cognitive Benefits
  • 41:31 Metabolic Flexibility and Performance
  • 44:42 Breath Work and Stress Regulation
  • 47:54 Balancing General Health and Specific Goals
  • 53:29 Conclusion and Where to Find Us

Check it out below and let me know you think!

Much love,
Dr Mike

_____________________

Mike T Nelson CISSN, CSCS, MSME, PhD
Associate Professor, Carrick Institute
Owner, Extreme Human Performance, LLC
Editorial Board Member, STRONG Fitness Mag

Mike T Nelson is a PhD and not a physician or registered dietitian. The contents of this email should not be taken as medical advice. It is not intended to diagnose, treat, cure, or prevent any health problem - nor is it intended to replace the advice of a physician. Always consult your physician or qualified health professional on any matters regarding your health.

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Dr Mike T Nelson

Creator of the Flex Diet Cert & Phys Flex Cert, CSCS, CISSN, Assoc Professor, kiteboarder, lifter of odd objects, metal music lover. >>>>Sign up to my daily FREE Fitness Insider newsletter below

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