I’ve talked about creatine on a LOT of podcasts this year, but this conversation with Paul Oneid went in some different directions. Paul is a strength coach who wants to know what the research actually means once you leave PubMed and have a real human standing in front of you. We covered: The origins of creatine How much creatine your muscles can actually store Why you do NOT need a loading phase Creatine and cognition Why creatinine can make your blood work look weird Creatine monohydrate...
2 days ago • 1 min read
Big milestone as we just reached episode 400 of the Flex Diet Podcast! I could not have done it without out, thank you! In this one I sit down with Dr. Dwayne Jackson, a PhD researcher in neurovascular physiology, exercise and human physiology, medicine, and nutritional biochemistry. We discuss why mitochondrial peptides such as MOTS-c and SS-31 may be promising tools, but cannot replace the aerobic base that makes their effects meaningful. We also dig into AMPK and mTOR signaling,...
3 days ago • 1 min read
Another Minnesota August week in the books—hopefully you found a little time to train, get outside, and avoid arguing with the internet about peptides. Haha I failed. This week there is plenty here to dig into, from BPC-157 data and more. Always curious as to what you think, so hit me back. Here's what went down this week: Newsletters: BPC-157 - your guide on me at no cost: A free, research-focused guide to what we know—and do not know—about BPC-157, including the surprisingly thin human...
5 days ago • 2 min read
I made a tactical error this week. I asked the internet what it thought about my BPC-157 PDF. I was hoping for: “Interesting. I hadn’t seen that human study.” “Good point about the animal data.” “I disagree with your conclusion because of X, Y, and Z.” What repeatedly arrived instead was some version of: “Why did you even make dis PDF? I KNOW BPC-157 works Bro! This is dumb.” Ah. Excellent. Thank you, Professor Double-Blind Randomized IG DMer. This is one of the strangest things about...
6 days ago • 3 min read
35 rat studies walk into a peptide clinic... ...and somehow a human walks out with a syringe. Welcome to the world of BPC-157. AKA the “Wolverine peptide,” and the internet’s favorite answer to every pissed-off tendon, cranky shoulder, mangled knee, and body part currently sending strongly worded letters to management. I’ve had a LOT of questions about it: Does it work? Can you take it orally? Is it safe? And what the hell happened with the FDA last week? Then there’s my favorite: “Dooode,...
8 days ago • 3 min read
In this episode of the Flex Diet Podcast, I sit down with Dr. Emily Werner, PhD, RD, CSSD, IFNCP — team dietitian for the Philadelphia 76ers (NBA) and Philadelphia Flyers (NHL), and Nutrition Affairs Sport Lead at Timeline. We dig into postbiotics, urolithin A, and why mitochondrial health matters for pro athletes and everyday people alike. Emily walks through the real research behind Timeline's Mitopure, how she navigates athlete psychology and supplement fads on the sidelines of pro sports,...
11 days ago • 1 min read
Greetings from Minnesota, where the mornings are finally starting to hint at that first crisp bite of fall — hands down my favorite time of year to be out banging around in the garage gym. Between updating / creating new programs for my online 1-1 M3 clients, writing, and even getting the ole cold plunge freezer dumped and cleaned, it has been a good week. Here's what went down this week: Newsletters: Top 5 Creatine Myths (full PDF): Busting the biggest creatine myths the internet keeps...
12 days ago • 3 min read
A few of you hit reply after yesterday’s creatine email with basically the same question: “Okay Dr Mike, what creatine do YOU use?” Easy. Creatine monohydrate from Driven Nutrition. I’ve used the same stuff for almost 12 years. Twelve. Years. Which is roughly 874 years in supplement-industry dog years where every six months somebody discovers a NEW ULTRA-BOLIC CREATINE that apparently makes boring old monohydrate look like it arrived on the Mayflower. Yet there it sits on my shelf. Creatine...
13 days ago • 1 min read
Every few years the internet tries to bury the supplement creatine under kidney panic, hair-loss hysteria, dehydration warnings, or some new rule handed down from a guy named Chad between his 7th sets of cable crossovers. Meanwhile, the actual research keeps ruining the story. For example… • The blood-test number that can suddenly look “bad” after starting creatine — even when your kidneys are perfectly fine. (p. 2) • Why your doctor may see elevated creatinine and reach for the wrong...
14 days ago • 1 min read